Science Signaling

Aims & Scope

Uncovering mechanisms in biology, gaining insights into physiology and disease Science Signaling is a weekly, online multidisciplinary journal for the life sciences.

The aim of the journal editors is to publish studies that uncover the basic mechanisms that underlie biological processes across all organisms.

Particular emphasis is placed on studies that provide new insights into physiology; delineate aberrant mechanisms that cause disease; identify new potential therapeutic targets and strategies; and characterize the effects of drugs in vitro and in vivo.

View Aims & Scope

---

Metrics & Ranking

Impact Factor

Year	Value
2025	6.6
2024	6.70

SJR (SCImago Journal Rank)

Year	Value
2024	2.143

Quartile

Year	Value
2024	Q1

h-index

Year	Value
2024	187

Journal Rank

Year	Value
2024	1267

Journal Citation Indicator

Year	Value
2024	2060

---

---

Abstracting & Indexing

Journal is indexed in leading academic databases, ensuring global visibility and accessibility of our peer-reviewed research.

• Scopus
• Google Scholar
• Web of Science
• Medline
• Embase

---

Subjects & Keywords

Journal’s research areas, covering key disciplines and specialized sub-topics in Biochemistry, Genetics and Molecular Biology, designed to support cutting-edge academic discovery.

---

Most Cited Articles

The Most Cited Articles section features the journal's most impactful research, based on citation counts. These articles have been referenced frequently by other researchers, indicating their significant contribution to their respective fields.

• Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

  Citation: 11323

  Authors: Jianjiong, Bülent Arman, Ugur, Gideon, Benjamin, S. Onur, Yichao, Anders, Rileen, Erik, Ethan, Chris, Nikolaus

• Quantitative Phosphoproteomics Reveals Widespread Full Phosphorylation Site Occupancy During Mitosis

  Citation: 1355

  Authors: Jesper V., Michiel, Anna, Chanchal, Martin L., Lars J., Florian, Jürgen, Thomas S., Erich A., Søren, Matthias

• Signaling mechanisms of the epithelial-mesenchymal transition

  Citation: 1340

  Authors: David M., Damian

• STING Specifies IRF3 Phosphorylation by TBK1 in the Cytosolic DNA Signaling Pathway

  Citation: 1101

  Authors: Yasuo, Zhijian J.

• Delivery of MicroRNA-126 by Apoptotic Bodies Induces CXCL12-Dependent Vascular Protection

  Citation: 1086

  Authors: Alma, Kiril, Heidi, Erdenechimeg, Lin, Bernd, Mihail, Thomas, Maliheh Nazari, Esther, Shusheng, Eric N., Andreas, Christian

• The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis

  Citation: 1071

  Authors: Agnes, Constance S., Florian, Sharon, Jennifer, Brittany, Tobias C., Shawn M.

• H ₂ S Signals Through Protein S-Sulfhydration

  Citation: 1005

  Authors: Asif K., Moataz M., Nilkantha, Seyun, Weitong, Sadia K., Roxanne K., Guangdong, Rui, Solomon H.

• CD36, a Scavenger Receptor Involved in Immunity, Metabolism, Angiogenesis, and Behavior

  Citation: 973

  Authors: Roy L., Maria

• Noncoding RNA Gas5 Is a Growth Arrest– and Starvation-Associated Repressor of the Glucocorticoid Receptor

  Citation: 867

  Authors: Tomoshige, Darrell E., Takamasa, Nancy, George P.

• The Plant NADPH Oxidase RBOHD Mediates Rapid Systemic Signaling in Response to Diverse Stimuli

  Citation: 862

  Authors: Gad, Karen, Rachel, Diego, Miguel A., Vladimir, Jeffery L., Ron

---