Aims & Scope

ACS Medicinal Chemistry Letters is interested in receiving manuscripts that discuss various aspects of medicinal chemistry.

The journal will publish studies that pertain to a broad range of subject matter, including compound design and optimization, biological evaluation, drug delivery, imaging agents, and pharmacology of both small and large bioactive molecules.

Specific areas include but are not limited to: Identification, synthesis, and optimization of lead biologically active molecules and drugs (small molecules and biologics) Biological characterization of new molecular entities in the context of drug discovery Computational, cheminformatics, and structural studies for the identification or SAR analysis of bioactive molecules, ligands and their targets, etc.

Novel and improved methodologies, including radiation biochemistry, with broad application to medicinal chemistry Discovery technologies for biologically active molecules from both synthetic and natural (plant and other) sources Pharmacokinetic/pharmacodynamic studies that address mechanisms underlying drug disposition and response Pharmacogenetic and pharmacogenomic studies used to enhance drug design and the translation of medicinal chemistry into the clinic Mechanistic drug metabolism and regulation of metabolic enzyme gene expression Chemistry patents relevant to the medicinal chemistry field.

View Aims & Scope

Metrics & Ranking

Impact Factor

Year Value
2025 4

Journal Rank

Year Value
2024 6721

Journal Citation Indicator

Year Value
2024 2575

SJR (SCImago Journal Rank)

Year Value
2024 0.805

Quartile

Year Value
2024 Q1

Impact Factor Trend


Abstracting & Indexing

Journal is indexed in leading academic databases, ensuring global visibility and accessibility of our peer-reviewed research.


Subjects & Keywords

Journal’s research areas, covering key disciplines and specialized sub-topics in Biochemistry, Genetics and Molecular Biology, Chemistry and Pharmacology, Toxicology and Pharmaceutics, designed to support cutting-edge academic discovery.


Quick Facts

Current Factor
4
First Published: 2025

SJR (SCImago Journal Rank)

SJR
0.805
First Published: 2024

Quartile

Current Quartile
Q1
First Published: 2024

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