Nature Methods

Aims & Scope

Nature Methods is a forum for the publication of novel methods and significant improvements to tried-and-tested basic research techniques in the life sciences.

This monthly publication is aimed at a broad, interdisciplinary audience of academic and industry researchers actively involved in laboratory practice.

It provides them with new tools to conduct their research and places a strong emphasis on the immediate practical relevance of the work presented.

The journal publishes primary research papers as well as overviews of recent technical and methodological developments.

We are actively seeking primary methods papers of relevance to the biological and biomedical sciences, including methods grounded in chemistry that have a practical application to the study of biological problems.

To enhance the practical relevance of each paper, description of the method must be accompanied by its validation, its application to an important biological question and results illustrating its performance in comparison to available approaches.

Articles are selected for publication that present broad interest, thorough assessments of methodological performance and comprehensive technical descriptions that facilitate immediate application.

View Aims & Scope

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Metrics & Ranking

Impact Factor

Year	Value
2025	32.1
2024	36.10

SJR (SCImago Journal Rank)

Year	Value
2024	17.251

Quartile

Year	Value
2024	Q1

h-index

Year	Value
2024	408

Journal Rank

Year	Value
2024	27

Journal Citation Indicator

Year	Value
2024	19073

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Abstracting & Indexing

Journal is indexed in leading academic databases, ensuring global visibility and accessibility of our peer-reviewed research.

• Scopus
• Google Scholar
• Web of Science
• Medline
• Embase

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Subjects & Keywords

Journal’s research areas, covering key disciplines and specialized sub-topics in Biochemistry, Genetics and Molecular Biology, designed to support cutting-edge academic discovery.

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Most Cited Articles

The Most Cited Articles section features the journal's most impactful research, based on citation counts. These articles have been referenced frequently by other researchers, indicating their significant contribution to their respective fields.

• Fiji: an open-source platform for biological-image analysis

  Citation: 59144

  Authors: Johannes, Ignacio, Erwin, Verena, Mark, Tobias, Stephan, Curtis, Stephan, Benjamin, Jean-Yves, Daniel James, Volker, Kevin, Pavel, Albert

• NIH Image to ImageJ: 25 years of image analysis

  Citation: 54687

  Authors: Caroline A, Wayne S, Kevin W

• Fast gapped-read alignment with Bowtie 2

  Citation: 48693

  Authors: Ben, Steven L

• QIIME allows analysis of high-throughput community sequencing data

  Citation: 29915

  Authors: J Gregory, Justin, Jesse, Kyle, Frederic D, Elizabeth K, Noah, Antonio Gonzalez, Julia K, Jeffrey I, Gavin A, Scott T, Dan, Jeremy E, Ruth E, Catherine A, Daniel, Brian D, Meg, Jens, Joel R, Peter J, William A, Jeremy, Tanya, Jesse, Rob

• SciPy 1.0: fundamental algorithms for scientific computing in Python

  Citation: 28878

  Authors: Pauli, Ralf, Travis E., Matt, Tyler, David, Evgeni, Pearu, Warren, Jonathan, Stéfan J., Matthew, Joshua, K. Jarrod, Nikolay, Andrew R. J., Eric, Robert, Eric, C J, İlhan, Yu, Eric W., Jake, Denis, Josef, Robert, Ian, E. A., Charles R., Anne M., Antônio H., Fabian, Paul, Aditya, Alessandro Pietro, Alex, Andreas, Andreas, Anthony, Antony, Ariel, C. Nathan, Chad, Charles, Christian, Clark, David A., David R., Dmitrii V., Emanuele, Eric, Eric, Fabrice, Felix, Florian, G., Gavin A., Gert-Ludwig, Gregory E., Gregory R., Hervé, Irvin, Jörg P., Jacob, James T, Janko, Joel, Johannes, Johannes, Johannes L., José Vinícius, Joscha, Joseph, Juan Luis Cano, Juan, Justin, Kevin, Martin, Matthew, Matthias, Maximilian, Michael, Mikhail, Nathaniel J., Nikolai, Nikolay, Oleksandr, Per A., Perry, Robert T., Roman, Sam, Sam, Scott, Sebastiano, Stefan, Surhud, Tadeusz, Takuya, Thomas J., Thomas P., Thomas, Thouis R., Tim, Tim, Tiziano, Tom, Utkarsh, Yaroslav O., Yoshiki

• DADA2: High-resolution sample inference from Illumina amplicon data

  Citation: 27353

  Authors: Benjamin J, Paul J, Michael J, Andrew W, Amy Jo A, Susan P

• HISAT: a fast spliced aligner with low memory requirements

  Citation: 19587

  Authors: Daehwan, Ben, Steven L

• UPARSE: highly accurate OTU sequences from microbial amplicon reads

  Citation: 14132

  Authors: Robert C

• ModelFinder: fast model selection for accurate phylogenetic estimates

  Citation: 14088

  Authors: Subha, Bui Quang, Thomas K F, Arndt, Lars S

• jModelTest 2: more models, new heuristics and parallel computing

  Citation: 14008

  Authors: Diego, Guillermo L, Ramón, David

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