Nature Chemical Biology

Aims & Scope

Nature Chemical Biology is an international monthly journal that provides a high-visibility forum for the publication of top-tier original research and commentary for the chemical biology community.

Chemical biology combines the scientific ideas and approaches of chemistry, biology and allied disciplines to understand and manipulate biological systems with molecular precision.

The journal publishes papers from the expanding community of chemical biologists, including contributions from chemists who are applying the principles and tools of chemistry to biological questions and from biologists who are interested in understanding and controlling biological processes at the molecular level.

View Aims & Scope

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Metrics & Ranking

Impact Factor

Year	Value
2025	13.7
2024	12.90

SJR (SCImago Journal Rank)

Year	Value
2024	5.521

Quartile

Year	Value
2024	Q1

h-index

Year	Value
2024	272

Journal Rank

Year	Value
2024	248

Journal Citation Indicator

Year	Value
2024	5919

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Abstracting & Indexing

Journal is indexed in leading academic databases, ensuring global visibility and accessibility of our peer-reviewed research.

• Scopus
• Google Scholar
• Web of Science
• Medline
• Embase

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Subjects & Keywords

Journal’s research areas, covering key disciplines and specialized sub-topics in Biochemistry, Genetics and Molecular Biology, designed to support cutting-edge academic discovery.

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Most Cited Articles

The Most Cited Articles section features the journal's most impactful research, based on citation counts. These articles have been referenced frequently by other researchers, indicating their significant contribution to their respective fields.

• N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

  Citation: 3436

  Authors: Guifang, Ye, Xu, Qing, Guanqun, Ying, Chengqi, Tomas, Tao, Yun-Gui, Chuan

• Network pharmacology: the next paradigm in drug discovery

  Citation: 3430

  Authors: Andrew L

• ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

  Citation: 3155

  Authors: Sebastian, Bettina, Yulia Y, Elena, Sho, Irina, Martin, Johannes, Michaela, Axel, Holger, Dietrich, Gaowei, Feng, Hulya, Joachim, Christina H, Wolfgang, Joel A, Valerian E, José Pedro Friedmann, Marcus

• A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

  Citation: 2823

  Authors: Jianzhao, Yanan, Dali, Xiao, Ye, Liang, Guifang, Miao, Zhike, Xin, Qing, Weizhong, Chuan

• Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

  Citation: 2553

  Authors: Alexei, Zhihong, Michael, Yaqiao, Prakash, Noboru, Gregory D, Timothy J, Michael A, Junying

• Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

  Citation: 2332

  Authors: Valerian E, Gaowei, Feng, Jose Pedro Friedmann, Sebastian, Claudette St, Haider Hussain, Bing, Vladimir A, Vladimir B, Alexandr A, Andrew A, Jianfei, Tamil, Dariush, Qin, Bettina, Judith, Simon, Ivet, Joel, Rama K, Brent R, Yulia Y, Marcus, Hülya

• Reconciling the chemistry and biology of reactive oxygen species

  Citation: 2108

  Authors: Christine C

• The role of iron and reactive oxygen species in cell death

  Citation: 2024

  Authors: Scott J, Brent R

• Networking by small-molecule hormones in plant immunity

  Citation: 1861

  Authors: Corné M J, Antonio, Sjoerd, Saskia C M

• Identification of RIP1 kinase as a specific cellular target of necrostatins

  Citation: 1756

  Authors: Alexei, Junichi, Megan, Irene L, Olga, Xin, Derek, Gregory D, Chengye, Gerhard, Stephen M, Scott A, Alexey, Junying

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