Journal of Pharmacokinetics and Pharmacodynamics

Aims & Scope

Broadly speaking, the Journal of Pharmacokinetics and Pharmacodynamics covers the area of pharmacometrics.

The journal is devoted to illustrating the importance of pharmacokinetics, pharmacodynamics, and pharmacometrics in drug development, clinical care, and the understanding of drug action.

The journal publishes on a variety of topics related to pharmacometrics, including, but not limited to, clinical, experimental, and theoretical papers examining the kinetics of drug disposition and effects of drug action in humans, animals, in vitro, or in silico; modeling and simulation methodology, including optimal design; precision medicine; systems pharmacology; and mathematical pharmacology (including computational biology, bioengineering, and biophysics related to pharmacology, pharmacokinetics, orpharmacodynamics).

Clinical papers that include population pharmacokinetic-pharmacodynamic relationships are welcome.

The journal actively invites and promotes up-and-coming areas of pharmacometric research, such as real-world evidence, quality of life analyses, and artificial intelligence.

The Journal of Pharmacokinetics and Pharmacodynamics is an official journal of the International Society of Pharmacometrics.

View Aims & Scope

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Metrics & Ranking

Impact Factor

Year	Value
2025	2.8
2024	2.20

Journal Rank

Year	Value
2024	5824

Journal Citation Indicator

Year	Value
2024	403

SJR (SCImago Journal Rank)

Year	Value
2024	0.887

Quartile

Year	Value
2024	Q2

h-index

Year	Value
2024	72

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Abstracting & Indexing

Journal is indexed in leading academic databases, ensuring global visibility and accessibility of our peer-reviewed research.

• Scopus
• Google Scholar
• Web of Science

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Subjects & Keywords

Journal’s research areas, covering key disciplines and specialized sub-topics in Pharmacology, Toxicology and Pharmaceutics, designed to support cutting-edge academic discovery.

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Most Cited Articles

The Most Cited Articles section features the journal's most impactful research, based on citation counts. These articles have been referenced frequently by other researchers, indicating their significant contribution to their respective fields.

• Ways to Fit a PK Model with Some Data Below the Quantification Limit

  Citation: 956

  Authors: Stuart L.

• General Pharmacokinetic Model for Drugs Exhibiting Target-Mediated Drug Disposition

  Citation: 522

  Authors: Donald E., William J.

• Implementation of a transit compartment model for describing drug absorption in pharmacokinetic studies

  Citation: 432

  Authors: Radojka M., Daniël M., Thomas, Mats O.

• Towards a platform PBPK model to characterize the plasma and tissue disposition of monoclonal antibodies in preclinical species and human

  Citation: 358

  Authors: Dhaval K., Alison M.

• Evaluating Pharmacokinetic/Pharmacodynamic Models Using the Posterior Predictive Check

  Citation: 355

  Authors: Yoshitaka, Stuart L., Lewis B.

• Simultaneous vs. Sequential Analysis for Population PK/PD Data I: Best-Case Performance

  Citation: 318

  Authors: Liping, Stuart L., Lewis B.

• Physiologically-based pharmacokinetic (PBPK) model to predict IgG tissue kinetics in wild-type and FcRn-knockout mice

  Citation: 290

  Authors: Amit, Joseph P.

• Likelihood based approaches to handling data below the quantification limit using NONMEM VI

  Citation: 284

  Authors: Jae Eun, Mats O., Adrian, Thomas M.

• Assessment of Actual Significance Levels for Covariate Effects in NONMEM

  Citation: 245

  Authors: Ulrika, E. Niclas, Mats O.

• Approximations of the target-mediated drug disposition model and identifiability of model parameters

  Citation: 234

  Authors: Leonid, Ekaterina, Tarundeep, Peiming

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