Journal of Biomolecular Screening

Aims & Scope

Advancing the Science of Drug Discovery: SLAS Discovery reports how scientists develop and utilize novel technologies and/or approaches to provide and characterize chemical and biological tools to understand and treat human disease.

SLAS Discovery is a peer-reviewed journal that publishes scientific reports that enable and improve target validation, evaluate current drug discovery technologies, provide novel research tools, and incorporate research approaches that enhance depth of knowledge and drug discovery success.

SLAS Discovery emphasizes scientific and technical advances in target identification/validation (including chemical probes, RNA silencing, gene editing technologies); biomarker discovery; assay development; virtual, medium- or high-throughput screening (biochemical and biological, biophysical, phenotypic, toxicological, ADME); lead generation/optimization; chemical biology; and informatics (data analysis, image analysis, statistics, bio- and chemo-informatics).

Review articles on target biology, new paradigms in drug discovery and advances in drug discovery technologies.

SLAS Discovery is of particular interest to those involved in analytical chemistry, applied microbiology, automation, biochemistry, bioengineering, biomedical optics, biotechnology, bioinformatics, cell biology, DNA science and technology, genetics, information technology, medicinal chemistry, molecular biology, natural products chemistry, organic chemistry, pharmacology, spectroscopy, and toxicology.

Abstracting & Indexing

Journal is indexed in leading academic databases, ensuring global visibility and accessibility of our peer-reviewed research.

• Scopus
• Google Scholar

Subjects & Keywords

Journal’s research areas, covering key disciplines and specialized sub-topics in Biochemistry, Genetics and Molecular Biology, Chemistry and Pharmacology, Toxicology and Pharmaceutics, designed to support cutting-edge academic discovery.

Most Cited Articles

The Most Cited Articles section features the journal's most impactful research, based on citation counts. These articles have been referenced frequently by other researchers, indicating their significant contribution to their respective fields.

• Adaptation of Aequorin Functional Assay to High Throughput Screening

  Citation: 77

  Authors: Emmanuel, Sunao, Yoshinori, Vincent J., Emmanuel, Michel

• Comparison of Assay Technologies for a Tyrosine Kinase Assay Generates Different Results in High Throughput Screening

  Citation: 20

  Authors: Matthew A., Donna, Quynhchi, Robert, Xiang, Jinzi J.

• Development and Evaluation of High Throughput Functional Assay Methods for hERG Potassium Channel

  Citation: 12

  Authors: Weimin, Jiesheng, Xiaying, David, Lin, Hong, Zhuyin, Damien, Tina

• High-Density Miniaturized Thermal Shift Assays as a General Strategy for Drug Discovery

  Citation: 12

  Authors: Michael W., Eugene C., Joseph D., Victor S., James, Edward, Ted, Eric, Barry A., Pamela, F.R.

• A Comparison of ALPHAScreen, TR-FRET, and TRF as Assay Methods for FXR Nuclear Receptors

  Citation: 10

  Authors: J. Fraser, Xiang, Robert, Chantal, Benjamin R., Yang, Matthew

• Validation of FLIPR Membrane Potential Dye for High Throughput Screening of Potassium Channel Modulators

  Citation: 5

  Authors: Kristi L., Sujatha M., Duncan, Char-Chang, Usha, David J., Michael J., Victoria E., Murali

• Selective Cytotoxicity Evaluation in Anticancer Drug Screening of Fractionated Plant Extracts

  Citation: 5

  Authors: Petra, Joachim, Per, Ulf, Senia, Anders, Rolf, Lars

• Cell-Based Versus Isolated Target Screening: How Lucky Do You Feel?

  Citation: 5

  Authors: Keith, Stephen

• Single-Molecule Detection Technologies in Miniaturized High Throughput Screening: Binding Assays for G Protein–Coupled Receptors Using Fluorescence Intensity Distribution Analysis and Fluorescence Anisotropy

  Citation: 5

  Authors: Martin, Ulrich, Keith J., Andrew J.

• High Throughput Prediction of Oral Absorption: Improvement of the Composition of the Lipid Solution Used in Parallel Artificial Membrane Permeation Assay

  Citation: 4

  Authors: Kiyohiko, Hirokazu, Minoru, Hidetoshi