Therapeutic Innovation and Regulatory Science

Aims & Scope

Therapeutic Innovation & Regulatory Science (TIRS) is the official scientific journal of DIA that strives to advance medical product discovery, development, regulation, and use through the publication of peer-reviewed original and review articles, commentaries, and letters to the editor across the spectrum of converting biomedical science into practical solutions to advance human health globally.

View Aims & Scope

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Metrics & Ranking

Impact Factor

Year	Value
2025	1.9
2024	2.00

SJR (SCImago Journal Rank)

Year	Value
2024	0.815

Quartile

Year	Value
2024	Q1

h-index

Year	Value
2024	54

Journal Rank

Year	Value
2024	6606

Journal Citation Indicator

Year	Value
2024	846

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Abstracting & Indexing

Journal is indexed in leading academic databases, ensuring global visibility and accessibility of our peer-reviewed research.

• Scopus
• Google Scholar
• Web of Science
• Medline
• Embase

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Subjects & Keywords

Journal’s research areas, covering key disciplines and specialized sub-topics in Medicine and Pharmacology, Toxicology and Pharmaceutics, designed to support cutting-edge academic discovery.

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Most Cited Articles

The Most Cited Articles section features the journal's most impactful research, based on citation counts. These articles have been referenced frequently by other researchers, indicating their significant contribution to their respective fields.

• Use of Medical Mobile Applications Among Hospital Pharmacists in Malaysia

  Citation: 406

  Authors: Long Chiau, Mohammed Abdul, Denlee David, Nur Amirah, Pauline Siew Mei, Muhammad Abdul, Yaser Mohammed Ali, Tahir Mehmood

• Partnering With Patients in the Development and Lifecycle of Medicines: A Call for Action

  Citation: 153

  Authors: Anton, James, Marc, Lode, Jan, Graeme, Angelika, Marilyn, Jeanne, Ifeanyi, Roslyn F., Veronica, Gervais

• Assessing the Financial Value of Patient Engagement: A Quantitative Approach from CTTI’s Patient Groups and Clinical Trials Project

  Citation: 120

  Authors: Bennett, Kenneth, Eric L., Michelle, Matthew, Sharon, Bray, Jamie N., Joseph

• Minimizing Patient Burden Through the Use of Historical Subject-Level Data in Innovative Confirmatory Clinical Trials: Review of Methods and Opportunities

  Citation: 102

  Authors: Jessica, Rosalind, Jiacheng, Jeen, Abhishek, Nicky, Andrew, Lisa, Josephine, Phil, Florence, Xiang, Ed

• The Use of External Controls in FDA Regulatory Decision Making

  Citation: 99

  Authors: Mahta, Keith, Gillian, Adora, Veronica, Jerry, Cecile, Tanja, Sharon

• Improving Patient Involvement in Medicines Research and Development: A Practical Roadmap

  Citation: 93

  Authors: Jan, Bettina, Susanna Leto, Mary

• Comprehensive In Vitro Proarrhythmia Assay (CiPA) Update from a Cardiac Safety Research Consortium / Health and Environmental Sciences Institute / FDA Meeting

  Citation: 90

  Authors: David G., Gary, Zhihua, Wendy, Ksenia, Jose, J. Rick, Philip T.

• Interpreting Change in Scores on Patient-Reported Outcome Instruments

  Citation: 88

  Authors: Cheryl D., Joseph C.

• Legal, Regulatory, and Practical Issues to Consider When Adopting Decentralized Clinical Trials: Recommendations From the Clinical Trials Transformation Initiative

  Citation: 83

  Authors: Maria, David, Amy, Annemarie, Gerrit, Jan, Laura, Vaishali, Penny

• A Review of Statistical Methods for Safety Surveillance

  Citation: 79

  Authors: Lan, Ted, Jyoti N., Ram C.

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