Molecular Therapy

Aims & Scope

Molecular Therapy is the leading international journal for research on the development of molecular and cellular therapeutics to correct genetic and acquired diseases, including but not limited to research on gene transfer and editing, vector development and design, stem cell manipulation, vaccine development, pre-clinical target validation, safety/efficacy studies, and clinical trials.

View Aims & Scope

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Metrics & Ranking

Impact Factor

Year	Value
2025	12
2024	12.10

SJR (SCImago Journal Rank)

Year	Value
2024	4.008

Quartile

Year	Value
2024	Q1

h-index

Year	Value
2024	220

Journal Rank

Year	Value
2024	419

Journal Citation Indicator

Year	Value
2024	8816

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Abstracting & Indexing

Journal is indexed in leading academic databases, ensuring global visibility and accessibility of our peer-reviewed research.

• Scopus
• Google Scholar
• Web of Science
• Medline
• PubMed
• Embase

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Subjects & Keywords

Journal’s research areas, covering key disciplines and specialized sub-topics in Biochemistry, Genetics and Molecular Biology, Medicine and Pharmacology, Toxicology and Pharmaceutics, designed to support cutting-edge academic discovery.

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Most Cited Articles

The Most Cited Articles section features the journal's most impactful research, based on citation counts. These articles have been referenced frequently by other researchers, indicating their significant contribution to their respective fields.

• Case Report of a Serious Adverse Event Following the Administration of T Cells Transduced With a Chimeric Antigen Receptor Recognizing ERBB2

  Citation: 2134

  Authors: Richard A, James C, Mio, Mark E, Carolyn M, Steven A

• Incorporation of Pseudouridine Into mRNA Yields Superior Nonimmunogenic Vector With Increased Translational Capacity and Biological Stability

  Citation: 1541

  Authors: Katalin, Hiromi, Frank A, János, Hiroki, Shizuo, Drew

• Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells

  Citation: 1411

  Authors: Shin-ichiro, Masakatsu, Katsuko, Shinobu, Akio, Nagahisa, Koji, Takayuki, Tadaaki, Takahiro, Noriko, Masahiko

• A Novel Nanoparticle Drug Delivery System: The Anti-inflammatory Activity of Curcumin Is Enhanced When Encapsulated in Exosomes

  Citation: 1350

  Authors: Dongmei, Xiaoying, Xiaoyu, Yuelong, Shuangyin, Cunren, Stephen, William, Donald, Huang-Ge

• Analysis of AAV Serotypes 1–9 Mediated Gene Expression and Tropism in Mice After Systemic Injection

  Citation: 1238

  Authors: Carmela, Stephen, Giuseppe, Joseph E

• Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain

  Citation: 1167

  Authors: Xiaoying, Xiaoyu, William, Dongmei, Shuangqin, Robert C, Songwen, Jiangyao, Lifeng, Lawrence, Donald, Huang-Ge

• Targeted Delivery of RNAi Therapeutics With Endogenous and Exogenous Ligand-Based Mechanisms

  Citation: 1039

  Authors: Akin, William, Soma, June, Maria, K. Narayanannair, Muthusamy, Kallanthottathil G, William L, J Robert, James S, LiuLiang, Timothy, Andrew, Eugenio, Anja, Michael J, Marino, Dinah WY, Kevin, Mark A, Muthiah, Victor, Antonin de, Martin A

• Chimeric Receptors Containing CD137 Signal Transduction Domains Mediate Enhanced Survival of T Cells and Increased Antileukemic Efficacy In Vivo

  Citation: 998

  Authors: Michael C., Jonathan D., Carmine, Richard G., Gwendolyn K., David, Minu, Mehdi, Brian, Gwenn, Dario, James L., Stephan A., Carl H.

• Mesenchymal Stem Cell-derived Extracellular Vesicles: Toward Cell-free Therapeutic Applications

  Citation: 983

  Authors: Sweta, Aideen E, Matthew D, Thomas

• A two-stage poly(ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy

  Citation: 949

  Authors: S. Moein, Peter, J. Clifford, A. Christy, Grazyna, Adam

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