Laboratory Investigation

Aims & Scope

Laboratory Investigation is an international journal owned by the United States and Canadian Academy of Pathology.

Laboratory Investigation offers prompt publication of high-quality original research in all biomedical disciplines relating to the understanding of human disease and the application of new methods to the diagnosis of disease.

Both human and experimental studies are welcome.

View Aims & Scope

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Metrics & Ranking

Impact Factor

Year	Value
2025	4.2
2024	5.10

SJR (SCImago Journal Rank)

Year	Value
2024	1.254

Quartile

Year	Value
2024	Q1

h-index

Year	Value
2024	170

Journal Rank

Year	Value
2024	3285

Journal Citation Indicator

Year	Value
2024	1988

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Abstracting & Indexing

Journal is indexed in leading academic databases, ensuring global visibility and accessibility of our peer-reviewed research.

• Scopus
• Google Scholar
• Web of Science

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Subjects & Keywords

Journal’s research areas, covering key disciplines and specialized sub-topics in Biochemistry, Genetics and Molecular Biology and Medicine, designed to support cutting-edge academic discovery.

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Most Cited Articles

The Most Cited Articles section features the journal's most impactful research, based on citation counts. These articles have been referenced frequently by other researchers, indicating their significant contribution to their respective fields.

• The role of shear stress in the pathogenesis of atherosclerosis

  Citation: 831

  Authors: Kristopher S, Avrum I

• Neutrophils: Molecules, Functions and Pathophysiological Aspects

  Citation: 781

  Authors: Véronique, Philippe, Béatrice, Philippe, Lise

• Programmed death ligand-1 expression in non-small cell lung cancer

  Citation: 617

  Authors: Vamsidhar, Kurt A, Daniel E, Valsamo K, Konstantinos N, Mario, Roy S, Scott N, Lieping, David L

• Validation of Tissue Microarray Technology in Breast Carcinoma

  Citation: 605

  Authors: Robert L, Lori A, David L

• CD68/macrosialin: not just a histochemical marker

  Citation: 583

  Authors: Dimitry A, Murry C, Veronika A, Alexander N, Yuri V

• Lipopolysaccharide signaling in endothelial cells

  Citation: 489

  Authors: Shauna M, Aly

• Immune microenvironment of gliomas

  Citation: 446

  Authors: Anna, Dominika, Kacper A, Wenson D, Bozena

• Diversity in cell surface sialic acid presentations: implications for biology and disease

  Citation: 429

  Authors: Nissi M, Ajit

• Normalization of gene expression measurements in tumor tissues: comparison of 13 endogenous control genes

  Citation: 426

  Authors: Jacques B, Rian W, Belinda A, Jeroen L, Erwin T, Ton, Dorine W, Paul N

• Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells

  Citation: 402

  Authors: Shyam, Roberto, Katri, Katherine L, Robert M, Thomas T, Jane E

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