Journal of Physiological Investigation

Aims & Scope

Journal of Physiological Investigation is a multidisciplinary open access journal.

Journal of Physiological Investigation (JPI) publishes high quality original research papers in physiology and pathophysiology by authors all over the world.

JPI welcomes submitted research papers in all aspects of physiology science in the molecular, cellular, tissue and systemic levels.

Multidisciplinary sciences with a focus to understand the role of physiology in health and disease are also encouraged.

Journal of Physiological Investigation​ accepts fourfold article types: Original Article, Review Article (Mini-Review included), Short Communication, and Editorial.

There is no cost for readers to access the full-text contents of publications.

Metrics & Ranking

Abstracting & Indexing

Journal is indexed in leading academic databases, ensuring global visibility and accessibility of our peer-reviewed research.

• Scopus
• Google Scholar
• Directory of Open Access Journals (DOAJ)

Subjects & Keywords

Journal’s research areas, covering key disciplines and specialized sub-topics in Biochemistry, Genetics and Molecular Biology and Medicine, designed to support cutting-edge academic discovery.

Licensing & Copyright

This journal operates under an Open Access model. Articles are freely accessible to the public immediately upon publication. The content is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0), allowing users to share and adapt the work with proper attribution.

Copyright remains with the author(s), and no permission is required for non-commercial use, provided the original source is cited.

Policy Links

This section provides access to essential policy documents, guidelines, and resources related to the journal’s publication and submission processes.

• Aims scope
• Homepage
• Oa statement
• Author instructions
• License terms
• Review url
• Board url
• Copyright url
• Plagiarism url
• Preservation url
• Apc url
• License

Plagiarism Policy

This journal follows a plagiarism policy. All submitted manuscripts are screened using reliable plagiarism detection software to ensure originality and academic integrity. Authors are responsible for proper citation and acknowledgment of all sources, and any form of plagiarism, including self-plagiarism, will not be tolerated.

For more details, please refer to our official: Plagiarism Policy.

APC Details

The journal’s Article Processing Charge (APC) policies support open access publishing in Biochemistry, Genetics and Molecular Biology and Medicine, ensuring accessibility and quality in research dissemination.

This journal requires an Article Processing Charge (APC) to support open access publishing, covering peer review, editing, and distribution. The current APC is 1,500.00 USD. Learn more.

Explore journals without APCs for alternative publishing options.

Most Cited Articles

The Most Cited Articles section features the journal's most impactful research, based on citation counts. These articles have been referenced frequently by other researchers, indicating their significant contribution to their respective fields.

• Cinnamaldehyde, A Bioactive Compound from the Leaves of Cinnamomum osmophloeum Kaneh, Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice by Inhibiting the NLRP3 Inflammasome

  Citation: 6

  Authors: May-Lan, Wei-Ting, Yih-Ming, Chen-Lung, Hsien-Ta, Kuo-Feng, Chun-Hsien, Lan-Hui

• Protective Effects of Trans-Chalcone on Myocardial Ischemia and Reperfusion Challenge through Targeting Phosphoinositide 3-kinase/Akt-inflammosome Interaction

  Citation: 6

  Authors: Jing, Shaik Althaf, Narendra, Haijun

• Allicin Mitigates Diabetic Retinopathy in Rats by Activating Phosphatase and Tensin Homolog-induced Kinase 1/Parkin-mitophagy and Inhibiting Oxidative Stress-mediated NOD-like Receptor Family Pyrin Domain Containing 3 Inflammasome

  Citation: 5

  Authors: Yuanyuan, Jia

• Association between Regular Exercise and Urinary Uric Acid Excretion in Chinese Adults: A Cross-sectional Study

  Citation: 4

  Authors: Wenjuan, Xiaoying, Yu, Miaomiao, Zilin, Shanhu

• Acute Hyperoxia Improves Spinal Cord Oxygenation and Circulatory Function Following Cervical Spinal Cord Injury in Rats

  Citation: 4

  Authors: Yen-Ting, Elisa J., Kun-Ze

• Elevations of N-Terminal Mid-Fragment of Osteocalcin and Cystatin C Levels are Associated with Disorders of Glycolipid Metabolism and Abnormal Bone Metabolism in Patients with Type 2 Diabetes Mellitus Complicated with Osteoporosis

  Citation: 4

  Authors: Xiaofang, Yun, Teng, Yan, Jie, Qianhong

• Neuroprotective Role of Transchalcone in Parkinson‘s Disease through AMP-activated Protein Kinase-mediated Signaling Pathway

  Citation: 4

  Authors: Yao, Shaik Althaf, Turki Mayudh, Xiaomin

• Protective Effect of Curcumin on the Tight Junction Integrity and Cellular Senescence in Human Retinal Pigment Epithelium of Early Diabetic Retinopathy

  Citation: 3

  Authors: Yu-Wen, Ya-Chih, Kai-Fu, Xiao-Fan, Gwo-Tarng, Nu-Man

• Overexpression of miR-204-5p Alleviates Osteogenic Differentiation and Calcification of Human Aortic Vascular Smooth Muscle Cells by Targeting Calcium/Calmodulin-dependent Protein Kinase 1

  Citation: 3

  Authors: Chunli, Mingzhi, Yafei, Mingjiao, Yonghui, Ruman

• Buyang Huanwu Decoction Alleviates Atherosclerosis by Regulating gut Microbiome and Metabolites in Apolipoprotein E-deficient Mice fed with High-fat Diet

  Citation: 2

  Authors: Qun, Yilin, Wenyun, Yingxin, Xiaolu, Lin, Yue, Bin, Maojuan, Yu, Huhu, Yanrong, Xijuan, Lili