Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Aims & Scope

The Journal of Chromatography B publishes papers on developments in separation science relevant to biology and biomedical research including both fundamental advances and applications.

Analytical techniques which may be considered include the various facets of chromatography, electrophoresis and related methods, affinity and immunoaffinity-based methodologies, hyphenated and other multi-dimensional techniques, and microanalytical approaches.

The journal also considers articles reporting developments in sample preparation, detection techniques including mass spectrometry, and data handling and analysis.

Developments related to preparative separations for the isolation and purification of components of biological systems may be published, including chromatographic and electrophoretic methods, affinity separations, field flow fractionation and other preparative approaches.

Applications to the analysis of biological systems and samples will be considered when the analytical science contains a significant element of novelty, e.g. a new approach to the separation of a compound, novel combination of analytical techniques, or significantly improved analytical performance.

Metrics & Ranking

Abstracting & Indexing

Journal is indexed in leading academic databases, ensuring global visibility and accessibility of our peer-reviewed research.

• Scopus
• Google Scholar
• Directory of Open Access Journals (DOAJ)
• Web of Science

Subjects & Keywords

Journal’s research areas, covering key disciplines and specialized sub-topics in Biochemistry, Genetics and Molecular Biology, Chemistry and Medicine, designed to support cutting-edge academic discovery.

Licensing & Copyright

This journal operates under an Open Access model. Articles are freely accessible to the public immediately upon publication. The content is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0), allowing users to share and adapt the work with proper attribution.

Copyright remains with the author(s), and no permission is required for non-commercial use, provided the original source is cited.

Policy Links

This section provides access to essential policy documents, guidelines, and resources related to the journal’s publication and submission processes.

• Aims scope
• Homepage
• Oa statement
• Author instructions
• License terms
• Review url
• Board url
• Copyright url
• Apc url
• License

Most Cited Articles

The Most Cited Articles section features the journal's most impactful research, based on citation counts. These articles have been referenced frequently by other researchers, indicating their significant contribution to their respective fields.

• Downstream processing of monoclonal antibodies—Application of platform approaches

  Citation: 753

  Authors: Abhinav A., Brian, Tim, Sam, Duncan

• Validation of bioanalytical LC–MS/MS assays: Evaluation of matrix effects

  Citation: 662

  Authors: Ann, Katrien, Sophie, Ilse, Yvette

• Analysis of nitrite and nitrate in biological fluids by assays based on the Griess reaction: Appraisal of the Griess reaction in the l-arginine/nitric oxide area of research

  Citation: 657

  Authors: Dimitrios

• Systematic and comprehensive strategy for reducing matrix effects in LC/MS/MS analyses

  Citation: 640

  Authors: Erin, Diane M., Ziling, Jeffrey R.

• Optimization of protein precipitation based upon effectiveness of protein removal and ionization effect in liquid chromatography–tandem mass spectrometry

  Citation: 586

  Authors: Cara, Pratibha, Bev, Vanaja, Russell

• Oxidative stress in brain aging, neurodegenerative and vascular diseases: An overview

  Citation: 535

  Authors: E., M.C., A., P.

• Oral bioavailability of curcumin in rat and the herbal analysis from Curcuma longa by LC–MS/MS

  Citation: 511

  Authors: Kuo-Yi, Lei-Chwen, Ting-Yu, Shau-Chun, Tung-Hu

• Standard line slopes as a measure of a relative matrix effect in quantitative HPLC–MS bioanalysis

  Citation: 488

  Authors: B.K.

• Linear regression for calibration lines revisited: weighting schemes for bioanalytical methods

  Citation: 480

  Authors: A.M, M.M, A.C

• Molecularly imprinted polymers: synthesis and characterisation

  Citation: 474

  Authors: Peter A.G, Amaia Zurutuza