Efficacy and Mechanism Evaluation

Aims & Scope

Abstracting & Indexing

Journal is indexed in leading academic databases, ensuring global visibility and accessibility of our peer-reviewed research.

• Directory of Open Access Journals (DOAJ)
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Subjects & Keywords

Journal’s research areas, covering key disciplines and specialized sub-topics in Health Professions and Medicine, designed to support cutting-edge academic discovery.

Licensing & Copyright

This journal operates under an Open Access model. Articles are freely accessible to the public immediately upon publication. The content is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0), allowing users to share and adapt the work with proper attribution.

Copyright remains with the author(s), and no permission is required for non-commercial use, provided the original source is cited.

Policy Links

This section provides access to essential policy documents, guidelines, and resources related to the journal’s publication and submission processes.

• Apc url
• Homepage
• Aims scope

APC Details

The journal’s Article Processing Charge (APC) policies support open access publishing in Health Professions and Medicine, ensuring accessibility and quality in research dissemination.

This journal does not charge a mandatory Article Processing Charge (APC). However, optional open access publication may incur fees based on the publisher’s policies. Learn more.

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Most Cited Articles

The Most Cited Articles section features the journal's most impactful research, based on citation counts. These articles have been referenced frequently by other researchers, indicating their significant contribution to their respective fields.

• Robotic-assisted surgery compared with laparoscopic resection surgery for rectal cancer: the ROLARR RCT

  Citation: 37

  Authors: David, Alessio, Helen, Julie, Neil, Joanne, Philip, Nicholas, Richard, Claire, Julia

• Evaluation of Array Comparative genomic Hybridisation in prenatal diagnosis of fetal anomalies: a multicentre cohort study with cost analysis and assessment of patient, health professional and commissioner preferences for array comparative genomic hybridisation

  Citation: 30

  Authors: Stephen C, Lyn S, Stephen, Talitha, Gareth, Diana G, Ruth, Claire, Jane, John A

• A randomised, double-blind, placebo-controlled trial of repeated nebulisation of non-viral cystic fibrosis transmembrane conductance regulator (CFTR) gene therapy in patients with cystic fibrosis

  Citation: 25

  Authors: Eric WFW, David K, Deborah, Katie J, Diana, Emily V, A Christopher, June, Ruaridh, Roberto, Paula, Mario, Seng H, David S, Steve, Heather E, Gwyneth, Jane C, Lee A, Maria H, Ann, Jackie, Natalie S, Hala I, Rosanna F, Jemyr, Sabrina, Duncan M, James SR, Deborah R, Andrew P, Uta, David M, Katharine, Tracy E, Samantha L, Stephen C, Laura, J Alastair, Joseph, Nancy, Brian F, Maria P, Paul, Alan W, Michelle C, Dominique, Michael, Gerry, Cuixiang, M Angeles, Hazel, Laura J, Gordon D, Andrew G, Tina, Javier, David J, Ian A, Emma K, Kamila M, Alexandra L, Gina, Clare J, Ronald K, Sarah, Nicholas J, Keith, Stephen N, Najwa, Samia, Emma J, Barbara J, Stephanie G, Minna, Rosa P, Michael D, Marguerite Y, James M, Paul

• REmote preconditioning for Protection Against Ischaemia–Reperfusion in renal transplantation (REPAIR): a multicentre, multinational, double-blind, factorial designed randomised controlled trial

  Citation: 24

  Authors: Raymond, Tim, Rosemary, Steven, Jennifer, Madhur, Kristin

• Intravitreal aflibercept compared with panretinal photocoagulation for proliferative diabetic retinopathy: the CLARITY non-inferiority RCT

  Citation: 17

  Authors: Sobha, Philip, A Toby, Joana, Amy, Jayashree, Caroline, Joanna, Rhiannon Tudor, Seow Tien, James, David, Beverley

• Amiloride, fluoxetine or riluzole to reduce brain volume loss in secondary progressive multiple sclerosis: the MS-SMART four-arm RCT

  Citation: 16

  Authors: Floriana, Peter, Richard A, Domenico, Anisha, Nevin, Jonathan, David, Ferran, Ian, Bhavana, Rebecca S, Frederik, Sebastien, Marie, Moira, Gina, Sue H, Sharmilee, Gavin, Claudia AM Gandini, Clive, Basil, Roger, Christopher J, Nigel, Siddharthan, Jeremy

• Defining phenotypes and treatment effect heterogeneity to inform acute respiratory distress syndrome and sepsis trials: secondary analyses of three RCTs

  Citation: 16

  Authors: Manu, Shalini, A Toby, Josie K, Timothy, Claire, Carolyn S, Kevin L, Pratik, Michael A, Jonathan, Cliona, John G, Anthony, Cecilia M, Daniel F

• A randomised placebo-controlled Phase III multicentre trial: low-dose intravenous immunoglobulin treatment for long-standing complex regional pain syndrome (LIPS trial)

  Citation: 15

  Authors: Andreas, Jatinder, Roy, Claire, Bernhard, Rima, Mairi, Joanna, Candy, Holly, Caroline, Nick, Ceri, Helen, Mark, Mick, Nick, Karim, Lynne, Gareth

• The REFLO-STEMI (REperfusion Facilitated by LOcal adjunctive therapy in ST-Elevation Myocardial Infarction) trial: a randomised controlled trial comparing intracoronary administration of adenosine or sodium nitroprusside with control for attenuation of microvascular obstruction during primary percutaneous coronary intervention

  Citation: 14

  Authors: Sheraz A, Jamal N, Islam Z, John P, Daniel J, Vijay, Martin, Keith R, Robert, AA Jennifer, Gerry P, Anthony H

• Sperm selection for assisted reproduction by prior hyaluronan binding: the HABSelect RCT

  Citation: 14

  Authors: Jackson, Sue, Yacoub, Sheena, Richard, Siladitya, Arri, Vinay, Daniel, Gordon, Robert, Allan, Kate, Rachel, Virginia, David