Drug Metabolism Letters

Aims & Scope

Continued as Drug Metabolism and Bioanalysis Letters.

Drug Metabolism Letters publishes letters, original research articles, mini-reviews, thematic issues based on mini-reviews and letters, commentaries, technical notes and drug clinical trial studies on major advances in all areas of drug metabolism and disposition.

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; bioactivation; recent developments for the identification of drug metabolites, reactive intermediate and glutathione conjugates.

Abstracting & Indexing

Journal is indexed in leading academic databases, ensuring global visibility and accessibility of our peer-reviewed research.

• Scopus
• Google Scholar

Subjects & Keywords

Journal’s research areas, covering key disciplines and specialized sub-topics in Biochemistry, Genetics and Molecular Biology, Medicine and Pharmacology, Toxicology and Pharmaceutics, designed to support cutting-edge academic discovery.

Most Cited Articles

The Most Cited Articles section features the journal's most impactful research, based on citation counts. These articles have been referenced frequently by other researchers, indicating their significant contribution to their respective fields.

• Efficiency in Drug Discovery: Liver S9 Fraction Assay As a Screen for Metabolic Stability

  Citation: 109

  Authors: Samantha, April, Ashutosh, Mehran

• An Examination of IC50 and IC50-Shift Experiments in Assessing Time-Dependent Inhibition of CYP3A4, CYP2D6 and CYP2C9 in Human Liver Microsomes

  Citation: 100

  Authors: Loren, Zhiyang

• Esterase Activities in the Blood, Liver and Intestine of Several Preclinical Species and Humans

  Citation: 96

  Authors: Loren, Lance, Zhiyang

• Renal and Hepatic Transporter Expression in Type 2 Diabetic Rats

  Citation: 73

  Authors: Jose, Michael, Lauren, Sharmilee, Ankur, Harihara

• Aldehyde Oxidase Activity and Inhibition in Hepatocytes and Cytosolic Fraction from Mouse, Rat,Monkey and Human

  Citation: 64

  Authors: Jasminder, Kishore, Chris

• Drug Confinement and Delivery in Ceramic Implants

  Citation: 62

  Authors: Maria, Francisco, Montserrat, Miguel

• Investigations Into the Drug-Drug Interaction Potential of Tapentadol in Human Liver Microsomes and Fresh Human Hepatocytes

  Citation: 62

  Authors: Christa, Rolf, Horst, Genfu

• Clinical Confirmation that the Selective JAK1 Inhibitor Filgotinib (GLPG0634) has a Low Liability for Drug-drug Interactions

  Citation: 53

  Authors: Florence, Julie, Annegret, Pille, Chantal, Gerben

• L-4F Differentially Alters Plasma Levels of Oxidized Fatty Acids Resulting in more Anti-Inflammatory HDL in Mice

  Citation: 48

  Authors: Satoshi, Victor, Mohamad, Brian, Alan, G.M., Alan, Srinivasa

• Glucuronidation of Buprenorphine and Norbuprenorphine by Human Liver Microsomes and UDP-Glucuronosyltransferases

  Citation: 48

  Authors: Yan, David