Clinical Trials

Aims & Scope

The journal is devoted to topics of generalizable interest to the clinical trials community in general and to clinical trials methodology in particular.

Topics that fall within the Aims and Scope of Clinical Trials include data management, trial logistics, design and conduct of trials, statistical methods, impact of trials on practice and policy, ethics, law and regulation, synthesis and evidence evaluation, history, education and training, patient-related issues, decision analysis, and commentaries on current or controversial issues.

The journal does not publish articles that essentially reproduce the protocol for an individual clinical trial.

Articles that simply report the results of a completed clinical trial are also not considered.

View Aims & Scope

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Metrics & Ranking

Impact Factor

Year	Value
2025	2.2
2024	2.20

SJR (SCImago Journal Rank)

Year	Value
2024	1.189

Quartile

Year	Value
2024	Q1

h-index

Year	Value
2024	79

Journal Rank

Year	Value
2024	3606

Journal Citation Indicator

Year	Value
2024	555

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Abstracting & Indexing

Journal is indexed in leading academic databases, ensuring global visibility and accessibility of our peer-reviewed research.

• Scopus
• Google Scholar
• Web of Science
• Medline
• Embase

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Subjects & Keywords

Journal’s research areas, covering key disciplines and specialized sub-topics in Medicine and Pharmacology, Toxicology and Pharmaceutics, designed to support cutting-edge academic discovery.

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Most Cited Articles

The Most Cited Articles section features the journal's most impactful research, based on citation counts. These articles have been referenced frequently by other researchers, indicating their significant contribution to their respective fields.

• An exploratory test for an excess of significant findings

  Citation: 537

  Authors: John PA, Thomas A

• The design and rationale of a multicenter clinical trial comparing two strategies for control of systolic blood pressure: The Systolic Blood Pressure Intervention Trial (SPRINT)

  Citation: 437

  Authors: Walter T, Kaycee M, Capri G, Dan R, Alfred K, William C, Lawrence J, David C, Karen C, Anthony A, Cora E, Suzanne, David M, Michael V, Joni K, Jeff D, Jackson T, Paul K

• Beyond the intention-to-treat in comparative effectiveness research

  Citation: 407

  Authors: Miguel A, Sonia

• Meta-analysis of individual patient data from randomized trials: a review of methods used in practice

  Citation: 405

  Authors: Mark C, Julian P T, Lesley A, Jayne F, Mike J, Simon G

• Are missing outcome data adequately handled? A review of published randomized controlled trials in major medical journals

  Citation: 398

  Authors: Angela M, Ian R, Simon G

• Key cost drivers of pharmaceutical clinical trials in the United States

  Citation: 324

  Authors: Aylin, Hui-Hsing, Amber, Trinidad

• Summarizing historical information on controls in clinical trials

  Citation: 296

  Authors: Beat, Gorana, Michael, David J

• Imputation methods for missing outcome data in meta-analysis of clinical trials

  Citation: 289

  Authors: Julian PT, Ian R, Angela M

• Unsuccessful trial accrual and human subjects protections: An empirical analysis of recently closed trials

  Citation: 279

  Authors: Benjamin, Jonathan, Tim, Nathalie

• Efficiencies of platform clinical trials: A vision of the future

  Citation: 250

  Authors: Benjamin R, Scott M

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