Aims & Scope
Cell Systems was established in 2015 to provide a home at Cell Press for elegant work that addresses fundamental questions in systems biology. "Systems biology," as we broadly define it, is work that develops a rigorous understanding of any biological phenomenon where one plus one does not apparently equal two.
Disciplines in the physical sciences have met this challenge for a long time, and we've found that our strongest papers tend to apply classic approaches taken in physics, engineering, mathematics, and computer science to salient biological questions.
Manuscripts describing discoveries, milestone achievements, broadly useful tools or resources, or insights into the use of technology may all be appropriate.
Cross-disciplinary studies that reveal general principles of systems are particularly welcome.
We believe it's our responsibility to ensure that the next generation of scientists can begin their work on solid ground.
Accordingly, we focus our review process on validity and scientific acuity, rather than more subjective feelings and opinions.
We also believe that scientific transparency is of paramount importance.
A study's structure and presentation should be candid and forthright (e.g. it should ensure fair comparisons; it should either use non-arbitrary cut-offs or clearly explained arbitrary cut-offs that do not affect outcomes; its data visualization choices should promote objective understanding; its limitations should not be obscured).
Fundamentally good scientific practice also demands that studies be repeatable.
We encourage authors to make their code and data FAIR—that is findable, accessible, interoperable, and reusable, as defined by the NIH Data Commons.
Although it is too early to formally require that all studies we publish be FAIR, we consider that requirement annually.
View Aims & ScopeMetrics & Ranking
Impact Factor
| Year | Value |
|---|---|
| 2025 | 7.7 |
| 2024 | 9.00 |
SJR (SCImago Journal Rank)
| Year | Value |
|---|---|
| 2024 | 4.943 |
Quartile
| Year | Value |
|---|---|
| 2024 | Q1 |
h-index
| Year | Value |
|---|---|
| 2024 | 98 |
Journal Rank
| Year | Value |
|---|---|
| 2024 | 297 |
Journal Citation Indicator
| Year | Value |
|---|---|
| 2024 | 2130 |
Impact Factor Trend
Abstracting & Indexing
Journal is indexed in leading academic databases, ensuring global visibility and accessibility of our peer-reviewed research.
Subjects & Keywords
Journal’s research areas, covering key disciplines and specialized sub-topics in Biochemistry, Genetics and Molecular Biology and Medicine, designed to support cutting-edge academic discovery.
Most Cited Articles
The Most Cited Articles section features the journal's most impactful research, based on citation counts. These articles have been referenced frequently by other researchers, indicating their significant contribution to their respective fields.
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The Molecular Signatures Database Hallmark Gene Set Collection
Citation: 10788
Authors: Arthur, Chet, Helga, Mahmoud, Jill P., Pablo
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DoubletFinder: Doublet Detection in Single-Cell RNA Sequencing Data Using Artificial Nearest Neighbors
Citation: 3215
Authors: Christopher S., Lyndsay M., Zev J.
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Juicer Provides a One-Click System for Analyzing Loop-Resolution Hi-C Experiments
Citation: 3186
Authors: Neva C., Muhammad S., Ido, Suhas S.P., Miriam H., Eric S., Erez Lieberman
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Scrublet: Computational Identification of Cell Doublets in Single-Cell Transcriptomic Data
Citation: 2118
Authors: Samuel L., Romain, Allon M.
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Juicebox Provides a Visualization System for Hi-C Contact Maps with Unlimited Zoom
Citation: 1918
Authors: Neva C., James T., Muhammad S., Ido, Jill P., Eric S., Erez Lieberman
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A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure
Citation: 1319
Authors: Maayan, Adrian, Samuel L., Aubrey L., Renaud, Amedeo, Jennifer Hyoje, Bridget K., Shai S., Allon M., Douglas A., Itai
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A Single-Cell Transcriptome Atlas of the Human Pancreas
Citation: 1178
Authors: Mauro J., Gitanjali, Dominic, Nathalie, Tim, Erik, Leon, Marten A., Francoise, Eelco J.P., Alexander
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Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines
Citation: 704
Authors: Kyle, Matthew H., Gordon, Kyle R., Cyriac, Chip, Julian, Singer, Kami E., Michael, Heidi J., Carolyn, Gad, David, Li, Samantha J., John A., Ina, Melpomeni, Martin L., Carolyn M., Heidi J., Roy, Zhining, Liming, Jean C., Jiashan (Julia), Sudha, Jia, Laxmi, Rashi, Todd, Qiang, Yunhu, Ye, Juok, Timothy, Scott, Nils, Gad, David I., Jaegil, Michael S., Pei, Sam, Michael S., Gordon, Doug, Hailei, Brady, Nyasha, Varsha, Theo, Roger, Kalle, Yuexin, Michael, Sheila, Ilya, Vesteinn, Wei, Rehan, Bradley M., Apurva M., Zhenlin, Rupa S., Anil, Jun, Han, Shiyun, Wenbin, Yiling, Gordon B., Kwok-Shing, Arvind, Michael, Jing, John N., Jiexin, Adam, Joshua, Debyani, Walid K., Ino, Jianjiong, Benjamin E., Zachary J., Ritika, Konnor, Marc, Augustin, Moriah G., Angelica, Sarah M., Ed, Francisco, Chris, Nikolaus, Robert, S. Onur, Yichao, Barry S., Jioajiao, Hongxin, Pavana, Myron, Paul, Christopher, Joshua M., Christopher K., Christina, D. Neil, Matthew D., Adrian, Miruna, Reanne, Denise, Rebecca, Eric, Noreen, Robert, Steven J.M., Katayoon, Darlene, Yussanne, Marco A., Michael, Richard A., Andrew J., Karen, A. Gordon, Sara, Jacqueline E., Payal, Angela, Nina, Kane, Tina, Ashton C., Rameen, Andrew D., Carrie, Stacey B., Galen F., Gavin, Matthew, Steven E., Juliann, Melanie H., Raju S., Stephen, Leslie, Ludmila, Moiz S., Phillip H., Dennis T., David J., Daniel J., J. Todd, Saianand, Tom, Cheng, Katherine A., Alan P., Stuart R., Corbin D., Shaowu, Piotr A., Lisle E., Amy H., Charles M., Jeffrey, Yan, Janae V., Tara, Matthew G., Donghui, Umadevi, Huihui, Toshinori, Peter W., Hui, Wanding, Michelle, Kyle, Kyle, Chad J., Huyen, HarshaVardhan, Lawrence A., Jennifer, Richard A., Robert, Walker, Yi, Jianhong, Viktoriya, Sandra, Lora, Wei, Xiuping, Margaret, Donna, Donna, Jireh, Margi, Eve, Linghua, Min, David A., Liu, Fengmei, Julian, Elizabeth L., Matthew, Matthew G., Li, Catrina C., Lucinda A., Robert S., Cyriac, Elaine R., Michael D., Christopher A., Heather K., Richard K., Daniel, Erin, Johanna, Kevin, David, Scott, Joseph, Robert, Candace, Troy, Mark, Eric, Peggy, Jay, Julie M., Mark, Kristen M., Tara M., Nilsa C., Lisa, Erik, Niall, Tony, Christopher, Andre L., Ana C., José H., Adhemar, Rui M., Cristovam, Henrique C.S., Daniel O., Andrew, Jennifer, Beth, Ardene, Rosy, Matthew L., Patricia D., Michael, David, Bernard, Xuan, Richard, Chris, Elizabeth R., Vladimir, Oxana, Galiya, Alexey, Mikhail, Christopher, Ronald, Ross, Daniel, Colleen, Neil, Adam, Michael, Chandrajit P., Andrei, Jill S., Wendi, Karen, Jordonna, Quinn T., Kristen, Yingli, Andrew E., Agostino, Felice, Marc, Beth Y., Curt H., John, Jodi, Jerome, Kelinda, Leigh Anne, Brenda, Hai, Leonid, Caroline, Richard J., Stella, Ales, Tomas, Joseph, Mary, Brenda, Patricia, Mathieu, Louis, Bernard, Alain, Mary, Susan M., John, Hanina, Antonia, Tao, Timothy, Olga, Olga, Laurence, Odette, Sergio, Xavier, Marc-Henri, Feixiong, Sabina, Andrew, Darell, Eric, Jeffrey, Shannon, Roger, Angeles, Alexis, Madhusmita, Daniel J., Amy, Keith, Seth, Fadlo, Kelly, Shishir, Jeffrey J., Taofeek, Alan, Suresh, Dong M., Gabriel, Erwin G., Hongzheng, Wil, Ad, Esther, Leendert, Wolter, Hans, Kim E., Ellen C., Chiara, Lucia, Stefania, Francesco, Gaetano, Luca, Alessandro, Bianca, Chu, John, Pawadee, Arndt, Christine, Robert, Helge, Sven, Bernd, Witold, Dawid, Maciej, Ki, W. Jeffrey, Julie, Eric, Glenn, Raphael, Assunta, William G., Steven, Tom, Houtan, Lisa, Nicolas, Marta, Elias, Eva, Armando López, Nguyen, Phan Thi, Bui Duc, Yufang, Howard, Kimberley, Peter R., John A., Hani, Hartmut, Teniola, Serghei, Dave, Keunsoo, Koo Jeong, Felix, Anne, Michael, Debra, Mitesh, Alan H., Erik, Vishal, John, John A., Michael, Thomas, Nasra, Thai, Michael, Jean-Pierre, Karla, Catherine, David, Daniel, Brian Patrick, Tushar, Gloria, Florencia, Michael, Lewis, Robert, Thomas, Melissa, R. Houston, Michael, Ju Dong, Lizhi, Fadi, Jaffer A., Ana Maria, Carmen, Jolanta, Russell, Bogdan, Bita, Junya, Jeffrey, Charles, Alexander J., Christopher, Funda, Cesar, Lois, David, Anil, Pheroze, Timothy, Patricia, Anne, Ignacio, Candace, Lauren, Peter, Valerie, Hojabr, Richard, Kenneth, Georgina, Graham, Michael, Robyn, Richard, Kerwin, Andrew, Jonathan, Maria, John, James, Hikmat, Timothy A., Ronald, Anuradha, Douglas A., Victor, Samuel, Bhuvanesh, Nguyen Viet, Thomas, Cyrus, Praveen, Paul, Judy, Jennifer, Howard, Joong-Won, Nguyen Phi, Electron, W. Marston, Adam R., Karel, Peter A., Mark, Laura S., Cathy D., Nicolas, Robert, Hannah, Marc, Chandra, Jonathan, Harvey, Natalia, Irina, Mircea, Inga, Adrian, Serghei, Ghenadie, Sergiu, Maria, Irina, Diana, Monique, Iakovina, Angel, John, Jay, Sebastien, Jeremy, Harman, George, Doris M., Robert C., Carlo, Raina, Walter, Nicholas, Henri, Anna, Francesco, Gianluca, Mirella, Roberta, Ronald, Anne-Paule, Alain, Simone, Ginette, Kivanc, Gene, Cathy, Carol, Theresa, Nathan A., Daniel, Cathy, Kathy, Felicia, Carl, Jeffrey A., Michael J., Mark, Christopher W., Kerstin, Larsson, Mikhail, George, Domenico, Maria Consiglia, Vincenzo, Guido, Eugenio, David, Sandra, Michael, Fedor, Renumathy, Karl-Friedrich, Klaus-Peter, Julia, Mohamed H., Dina, Sue, Colleen M., Amy, Rebecca, J. Bradley, Joe, Bahavna, James, Norman L., Randy, Phuong, Robert, Karan, Lynn, Kelly, Paul, Paul, Ronald, James, Arthur, William E., Katherine C., Alison, Joel, Sima, Jens, Martin, Sylvia L., Dirk, Marta, Markus, Hartwig, Guido, Thorsten, Ronald, Pierre, Oluwole, Mark, Oliver, Peter R., June M., Philip, Pat, Robin K., Charles N., Joanna, Michael, Jeffry, Karen, Scott, Kevin, Ashley, Ady, Suzanne, Ruth, Antonio, Francis, Ian, Massimo, Michael, Brenda, Benito, Christel, Christin, Andreas, Andreas, Aaron, Joseph, Laura, Michael, Tina, Deqin, Mohammed, Rita, Andrew K., Rashna, Howard G., Clement, Sally N., Alex, David, Thomas, Anne-Marie, Fred, Therese, Lisa, Robert, Kathleen, Katherine, Russel, Joan, Rosemary, Michael, Federico, Rajiv, James, Edna M., Mario, Carlos Gilberto, Jose Sebastião, Rafael, Ajith, Daniela, James, Kathy, Elizabeth, Jenette, Bruce, Carl Simon, Eryn M., Sara, Cassaundra, Carol, Thomas, Andrea, Jeffey, Lisa, Mark, Laura, Gregory, Rayleen, Kwun M., Ian, Robert, W. Kimryn, J. Leigh, Jeffrey A., Albert J., Craig D., John, Bettina, Ramaswamy, Sharon, Timothy, Brian, Peter, Mark A., Jung Il, Natália D., Armaz
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Plasma Proteome Profiling to Assess Human Health and Disease
Citation: 607
Authors: Philipp E., Nils A., Garwin, Lesca M., Daniel, Matthias
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Construction and Analysis of Two Genome-Scale Deletion Libraries for Bacillus subtilis
Citation: 569
Authors: Byoung-Mo, George, Jeremiah D., Horia, Kenneth, Harvey, Ilan, Marco, Angelo, Jason M., Anna-Barbara, David Z., Karen N., Athanasios, Carol A.