Archives of Toxicology

Aims & Scope

The Archives of Toxicology aim to promote our understanding of toxic as well as pathophysiological mechanisms relevant to the mode of action of chemicals on human and mammalian cells and organisms.

Particularly welcome are Short Communications, Review Articles, Original Articles, and Commentaries that focus on: molecular mechanisms of toxic substances; in vitro techniques for toxicity testing and regulatory toxicology; advances in "omics" techniques for identification and classification of toxic substances; mechanisms and relevance of metabolic activation and inactivation

View Aims & Scope

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Metrics & Ranking

Impact Factor

Year	Value
2025	6.9
2024	4.80

Journal Rank

Year	Value
2024	2514

Journal Citation Indicator

Year	Value
2024	4205

SJR (SCImago Journal Rank)

Year	Value
2024	1.456

Quartile

Year	Value
2024	Q1

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Abstracting & Indexing

Journal is indexed in leading academic databases, ensuring global visibility and accessibility of our peer-reviewed research.

• Scopus
• Google Scholar
• Web of Science
• Medline
• Embase

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Subjects & Keywords

Journal’s research areas, covering key disciplines and specialized sub-topics in Environmental Science, Medicine and Pharmacology, Toxicology and Pharmaceutics, designed to support cutting-edge academic discovery.

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Most Cited Articles

The Most Cited Articles section features the journal's most impactful research, based on citation counts. These articles have been referenced frequently by other researchers, indicating their significant contribution to their respective fields.

• Antioxidants and antioxidant methods: an updated overview

  Citation: 1588

  Authors: Ä°lhami

• A new approach to practical acute toxicity testing

  Citation: 1516

  Authors: Dietrich

• Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging

  Citation: 1420

  Authors: Klaudia, Renata, Suliman Y., Saleh H., Eugenie, Kamil, Marian

• Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosis

  Citation: 1404

  Authors: Krishnendu, Joydeep, Pabitra Bikash, Parames C.

• Antioxidant activity of food constituents: an overview

  Citation: 1243

  Authors: Ä°lhami

• Toxicity of Ag, CuO and ZnO nanoparticles to selected environmentally relevant test organisms and mammalian cells in vitro: a critical review

  Citation: 1075

  Authors: Olesja, Katre, Angela, Kaja, Monika, Anne

• Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

  Citation: 1050

  Authors: Patricio, Nicola J., Ute, Melvin E., Nariman, Sudin, Johannes Georg, Jennifer, Christoph, Jan, Albert, Robert A., Britta, Neil R., Giovanni, Chong-Su, Yun-Jaie, J., Uta, Georg, Olaf, María Teresa, Jian, Steven, Dirk, Rowena, Karine Sá, Valentina, Joanna, Rolf, Andrew, Matthias, Chris E. P., María José, Geny M. M., Lena, Christelle, David, Seddik, Adam, Dieter, Claus, Philip, Stefan, Hermann-Georg, J. Brian, Jens, Kiyomi, Hartmut, Verena, Jens M., B., Claus, Gerd A., Edward L., Peng, Jennifer, Anna, Daniel J., Madlen, Patrick, Irmgard, Simon, Christoph, Jessica, Dean J., Andreas K., Peter, Francesco, Jingbo, Linda, Stefan A., Anup, Vera, Cliff, Celine, Kathrin, Michael, Bijay, Ernst H. K., Bruno, Regina, Yuichi, Ciro, Wolfgang E., Tamara, Mathieu, Thomas S., Agata, Courtney G., Jinghai James, Kathy M., Jan G.

• Carcinogenic metal compounds: recent insight into molecular and cellular mechanisms

  Citation: 944

  Authors: Detmar, Andrea

• Compromised MAPK signaling in human diseases: an update

  Citation: 854

  Authors: Eun Kyung, Eui-Ju

• The cytoprotective role of the Keap1–Nrf2 pathway

  Citation: 847

  Authors: Liam, Albena T.

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