American Journal of Physiology - Heart and Circulatory Physiology

Aims & Scope

The American Journal of Physiology-Heart and Circulatory Physiology publishes original investigations, reviews and perspectives on the physiology of the heart, vasculature, and lymphatics.

These articles include experimental and theoretical studies of cardiovascular function at all levels of organization ranging from the intact and integrative animal and organ function to the cellular, subcellular, and molecular levels.

The journal embraces new descriptions of these functions and their control systems, as well as their basis in biochemistry, biophysics, genetics, and cell biology.

Preference is given to research that provides significant new mechanistic physiological insights that determine the performance of the normal and abnormal heart and circulation.

View Aims & Scope

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Metrics & Ranking

Impact Factor

Year	Value
2025	4.1
2024	4.10

SJR (SCImago Journal Rank)

Year	Value
2024	1.464

Quartile

Year	Value
2024	Q1

Journal Rank

Year	Value
2024	2500

Journal Citation Indicator

Year	Value
2024	2828

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Abstracting & Indexing

Journal is indexed in leading academic databases, ensuring global visibility and accessibility of our peer-reviewed research.

• Scopus
• Google Scholar
• Web of Science
• Embase

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Subjects & Keywords

Journal’s research areas, covering key disciplines and specialized sub-topics in Biochemistry, Genetics and Molecular Biology and Medicine, designed to support cutting-edge academic discovery.

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Most Cited Articles

The Most Cited Articles section features the journal's most impactful research, based on citation counts. These articles have been referenced frequently by other researchers, indicating their significant contribution to their respective fields.

• Physiological time-series analysis using approximate entropy and sample entropy

  Citation: 5929

  Authors: Joshua S., J. Randall

• Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioning

  Citation: 1480

  Authors: Zhi-Qing, Joel S., Michael E., Faraz, Ning-Ping, Robert A., Jakob

• Assessment of flow-mediated dilation in humans: a methodological and physiological guideline

  Citation: 1163

  Authors: Dick H. J., Mark A., Kyra E., Jaume, Greg, Ryan A., Beth, Michael E., Michael E., Daniel J.

• A model for human ventricular tissue

  Citation: 1040

  Authors: K. H. W. J., D., P. J., A. V.

• Oxidative stress and heart failure

  Citation: 971

  Authors: Hiroyuki, Shintaro, Shouji

• Alternans and spiral breakup in a human ventricular tissue model

  Citation: 873

  Authors: K. H. W. J., A. V.

• Determination of layer-specific mechanical properties of human coronary arteries with nonatherosclerotic intimal thickening and related constitutive modeling

  Citation: 783

  Authors: Gerhard A., Gerhard, Christian T., Peter

• Mechanotransduction and endothelial cell homeostasis: the wisdom of the cell

  Citation: 715

  Authors: Shu

• Assessment of autonomic function in humans by heart rate spectral analysis

  Citation: 689

  Authors: B., R. J., M. A., I., D., D., K. M., A. C., D. C., R. J., al.

• High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents

  Citation: 651

  Authors: Junyi, Liang, Steve J., Blake D., James A., Timothy J., Kyle L., Bradley J., Craig T.

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