American Journal of Physiology - Gastrointestinal and Liver Physiology

Aims & Scope

The American Journal of Physiology-Gastrointestinal and Liver Physiology publishes original articles pertaining to all aspects of research involving normal or abnormal function of the gastrointestinal tract, hepatobiliary system, and pancreas.

Authors are encouraged to submit manuscripts dealing with growth and development, digestion, secretion, absorption, metabolism, and motility relative to these organs, as well as research reports dealing with immune and inflammatory processes and with neural, endocrine, and circulatory control mechanisms that affect these organs.

View Aims & Scope

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Metrics & Ranking

Impact Factor

Year	Value
2025	3.3
2024	3.90

SJR (SCImago Journal Rank)

Year	Value
2024	1.390

Quartile

Year	Value
2024	Q1

Journal Rank

Year	Value
2024	2735

Journal Citation Indicator

Year	Value
2024	1488

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Abstracting & Indexing

Journal is indexed in leading academic databases, ensuring global visibility and accessibility of our peer-reviewed research.

• Scopus
• Google Scholar
• Web of Science
• Embase

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Subjects & Keywords

Journal’s research areas, covering key disciplines and specialized sub-topics in Biochemistry, Genetics and Molecular Biology and Medicine, designed to support cutting-edge academic discovery.

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Most Cited Articles

The Most Cited Articles section features the journal's most impactful research, based on citation counts. These articles have been referenced frequently by other researchers, indicating their significant contribution to their respective fields.

• Inflammation and Cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation

  Citation: 981

  Authors: Steven H., Xianyang

• The adherent gastrointestinal mucus gel layer: thickness and physical state in vivo

  Citation: 784

  Authors: C., V., A., L.

• Propensity to high-fat diet-induced obesity in rats is associated with changes in the gut microbiota and gut inflammation

  Citation: 739

  Authors: Claire Barbier, Collin L., Jennifer, Amber L., John C., Helen E.

• TNF-α-induced increase in intestinal epithelial tight junction permeability requires NF-κB activation

  Citation: 716

  Authors: Thomas Y., Gary K., Neil T., Vimesh, Ali, Michel A., Hamid M.

• Increased intestinal permeability in obese mice: new evidence in the pathogenesis of nonalcoholic steatohepatitis

  Citation: 662

  Authors: Paola, Ignazio, Vincenza Di, Andrea, Massimo, Giorgio, Diego

• Molecular mechanisms of hepatic ischemia-reperfusion injury and preconditioning

  Citation: 658

  Authors: Hartmut

• Lipid Metabolism and Liver Inflammation. II. Fatty liver disease and fatty acid oxidation

  Citation: 643

  Authors: Janardan K., M.

• Colonic microbiome is altered in alcoholism

  Citation: 628

  Authors: Ece A., Patrick M., Huzefa, Masoumeh, Ammar, Phillip A., Mary, Cynthia K., Ali

• Probiotic bacteria and intestinal epithelial barrier function

  Citation: 595

  Authors: Christina L., Wallace K.

• Mechanisms of Liver Injury. I. TNF-α-induced liver injury: role of IKK, JNK, and ROS pathways

  Citation: 567

  Authors: Robert F., David A.

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